New drugs for coronavirus are required.

As the COVID pandemic started scientists from different countries started working on the drug for it. You all must have heard lots of names before but you know how the scientists work and how the new drug which going is going to be discovered works, that's what we are going to talk about today.

How we approached earlier

Sars CoV and Sars CoV-2 both show many similarities like replication and receptor binding affinity. As virus enters inside the body it has only one job i.e. replication. And so it starts making it's own copy. There is a drug known as "Ramdesivir" which inhibits the replication. But this was not much effective as it only helped patients to treat themselves faster.

Block the entry point

Now scientist approach by the method which blocks the entry of coronavirus in the body of the human, But how does this work? Actually coronavirus enters inside the body through receptors or the membranes. Almost all the receptor of human or animal origin are susceptible to the virus, The coronavirus enters through route relieson a protein cutting enzyme called TMPRSS2. So what would happen actually if we stop the enzyme?? Yes you are correct we can stop the deadly coronavirus from entry!

Now the question is, 'Can this happen?'. The answer is "YES". A drug named Camostat mesylate stops this enzyme and BLOCKS the entry of coronavirus.

But what after this? What if this drug cannot stop all the viruses but only stop the majority of them, because we know viruses replicate and even an amount as little as hundreds of the virus is very dangerous. So now our plan becomes to stop it's replication but HOW? Here enters the drug Ramdesivir. It was given intravenously, but due to limited supply and increasing demand, scientists also worked on a similar drug named 'Favipiravir'. It's a pill form of drug and is given to a person orally.

So is there any firm and final conclusion to this? Maybe no or maybe yes. It is because we people only hear about drugs being made for this deadly virus but what we see is the daily spike in the number of infected cases of covid19. We can only hope for the best and it is our responsibility to try as much as possible to protect ourselves and the people around us from this virus.

And Always remember the famous quotes : "Don't die of ignorance" and "Prevention is better than cure".

Thank You.

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