Corbevax is being said as a game-changer in this covid-19 era. As we all know for the last 2 years this virus has created havoc in the whole world. Even now when most of the people in this world are vaccinated still there is a terror of this virus, but the question is, are all people in this world are vaccinated? the answer is no. Wealthy countries are now giving booster shots but the financially struggling countries are still not able to give even the first dose to their people. This difference can be said a vaccination gap. So with the hope to decrease this gap and overcome this deadly pandemic corbevax is developed.
DEVELOPMENT OF CORBEVAX
Corbevax has been developed by Texas Children's Hospital for vaccine development and Bayor College of medicine by medical researchers Peter Hotez and Maria Elena. In 2003 when a strain of coronavirus known as SARS was identified these researchers created a vaccine using protein subunit technology and according to Hotez this is the same technology used in Hepatitis-B. Again a new strain of coronavirus broke out in this pandemic so these two thought to modify their old technology and can be used to curb covid-19 and CORBEVAX was developed.
WORKING PRINCIPLE OF CORBEVAX
In a protein sub-unit technology involvement of proteins from virus or bacterium induces response without causing any disease. Corbevax uses a harmless spike protein from the coronavirus which causes COVID-19 and helps the immune system to prepare for encounters with the virus.
A large U.S Based clinical trial found the vaccine to be safe and effective mostly in preventing symptomatic cases. In India, this vaccine received emergency use authorization and its production and development is being done in Biological E.limited(BioE)
A COVID VACCINE THAT ENCOMPASSES ALL
Corbevax is made according to global needs so this vaccine is cheap and is accessible to all countries. This vaccine can be produced at a larger scale because all the manufacturing facilities are already available. On the other hand, mRNA vaccines use newer technologies, are expensive, and work with a complicated process. The Indian government has ordered 300 million doses of corbevax and 1billion doses to be produced by BioE.
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